Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 8/20 | 0.58 |
| ▸ | RAB9A | P51151 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7116824 | 0.84 | TGM2 (0.54) | TGM2NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL3230113 | 0.82 | SMN1; SMN2 (0.59) | TGM2NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL25855377 | 0.81 | RAB9A (0.50) | NPC1RAB9ASMN1; SMN2LMNAPOLB | |
| SCHEMBL5073940 | 0.81 | TGM2 (0.54) | TGM2NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL23409950 | 0.81 | MAPT (0.45) | TGM2NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL9508841 | 0.81 | CASP1 (0.52) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL24341135 | 0.81 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2HPGDTP53 | |
| SCHEMBL7556396 | 0.80 | NPC1 (0.69) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL160077 | 0.80 | NPC1 (0.54) | TGM2NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL23629625 | 0.80 | NAMPT (0.50) | NPC1RAB9ASMN1; SMN2L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5621084-A | Process for removal of allyl group or allyloxycarbonyl group | PFIZER INC. (US) | 1997-04-15 | — | — | US | disclosed |
| EP-0676236-A1 | Process for removal of allyl group or allyloxycarbonyl group | PFIZER INC. (US) | 1995-10-11 | — | — | EP | disclosed |