Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8873335 | 0.92 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL8873865 | 0.87 | AGTR1 (0.47) | AGTR1AGTR2ACHE | |
| SCHEMBL8873855 | 0.86 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL8872976 | 0.85 | AGTR1 (0.47) | AGTR1AGTR2ACHE | |
| SCHEMBL8872214 | 0.85 | AGTR1 (0.45) | AGTR1AGTR2ACHE | |
| SCHEMBL8873549 | 0.80 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL8958794 | 0.80 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9016503 | 0.79 | AGTR1 (0.48) | AGTR1AGTR2ACHE | |
| SCHEMBL8359904 | 0.79 | ACHE (0.44) | AGTR1AGTR2ACHE | |
| SCHEMBL8872809 | 0.78 | SLC6A3 (0.45) | AGTR1AGTR2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618969-A | Intermediates for imidazopyridines | EISAI CO., LTD. (JP) | 1997-04-08 | — | — | US | disclosed |
| US-5587504-A | Sulfonyloxy-biphenylcarboxylic ester derivatives which are intermediates | EISAI CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| US-5559236-A | Intermediates for substituted biphenylmethylmidazopyridine angiotensin II antagonists | EISAI CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| US-5554757-A | Process for the preparation of imidazopyridine derivatives, and intermediates therefore | EISAI CO., LTD. (JP) | 1996-09-10 | — | — | US | disclosed |