Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CPT2 | P23786 | 1/20 | 0.36 |
| ▸ | CPT1A | P50416 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546974 | 0.91 | GRIN2B (0.40) | LMNAGRIN2BKCNH2ALDH1A1ATM | |
| SCHEMBL8541676 | 0.86 | GRIN2B (0.56) | LMNAGRIN2BKCNH2ALDH1A1ATM | |
| SCHEMBL8543096 | 0.84 | GRIN2B (0.47) | LMNAGRIN2BKCNH2ALDH1A1ATM | |
| SCHEMBL8544371 | 0.83 | GRIN2B (0.47) | GRIN2BKCNH2ALDH1A1ATMKMT2A | |
| SCHEMBL8548698 | 0.83 | GRIN2B (0.47) | GRIN2BKCNH2ALDH1A1ATMKMT2A | |
| SCHEMBL8547693 | 0.83 | GRIN2B (0.47) | GRIN2BKCNH2ALDH1A1ATMKMT2A | |
| SCHEMBL8545550 | 0.79 | GRIN1 (0.45) | LMNAGRIN2BKCNH2ALDH1A1CPT1A | |
| SCHEMBL8547856 | 0.79 | ALDH1A1 (0.55) | LMNAGRIN2BALDH1A1CPT2CPT1A | |
| SCHEMBL8540835 | 0.78 | GRIN2B (0.51) | LMNAGRIN2BALDH1A1 | |
| SCHEMBL8548421 | 0.78 | LMNA (0.43) | LMNAGRIN2BALDH1A1ATMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698553-A | Benzylpiperidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-12-16 | — | — | US | disclosed |