Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 10/20 | 0.41 |
| ▸ | VEGFA | P15692 | 4/20 | 0.41 |
| ▸ | FLT1 | P17948 | 4/20 | 0.41 |
| ▸ | EGLN3 | Q9H6Z9 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875475 | 0.90 | P4HTM (0.39) | PTGS2SMN1; SMN2LMNAHPGDHTT | |
| SCHEMBL8918674 | 0.89 | EGLN1 (0.46) | EGLN1VEGFAFLT1EGLN3SMN1; SMN2 | |
| SCHEMBL8106135 | 0.87 | LMNA (0.40) | PTGS2SMN1; SMN2LMNAHPGDHTT | |
| SCHEMBL8875047 | 0.87 | SMN1; SMN2 (0.36) | PTGS2SMN1; SMN2LMNAHPGDHTT | |
| SCHEMBL8874117 | 0.83 | P4HTM (0.38) | PTGS2SMN1; SMN2HTTEGFRKMT2A | |
| SCHEMBL8875576 | 0.82 | MAPT (0.49) | EGLN1PTGS2LMNAEGFRKMT2A | |
| SCHEMBL8875242 | 0.82 | LIMK1 (0.39) | PTGS2SMN1; SMN2HTTEGFRKMT2A | |
| SCHEMBL8873747 | 0.82 | LMNA (0.44) | SMN1; SMN2LMNAHTTKMT2A | |
| SCHEMBL8875238 | 0.81 | MEN1 (0.44) | KMT2AP4HTM | |
| SCHEMBL8096944 | 0.80 | SMN1; SMN2 (0.39) | PTGS2SMN1; SMN2LMNAHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620996-A | Sulfonamidocarbonyl pyridine-2-carboxesteramides and their pyridine-N-oxide compounds and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-04-15 | — | — | US | disclosed |