Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8874117 | 0.93 | P4HTM (0.38) | P4HTMSMN1; SMN2PTGS2HTTKMT2A | |
| SCHEMBL8875242 | 0.93 | LIMK1 (0.39) | P4HTMSMN1; SMN2PTGS2HTTKMT2A | |
| SCHEMBL8875238 | 0.92 | MEN1 (0.44) | P4HTMCYP1A2HSP90AA1HSP90AB1BLM | |
| SCHEMBL8916746 | 0.90 | EGLN1 (0.42) | P4HTMCYP1A2HSP90AA1HSP90AB1BLM | |
| SCHEMBL8875047 | 0.90 | SMN1; SMN2 (0.36) | P4HTMSMN1; SMN2PTGS2HTTLMNA | |
| SCHEMBL8873580 | 0.90 | EGLN1 (0.41) | P4HTMSMN1; SMN2PTGS2HTTLMNA | |
| SCHEMBL8875237 | 0.89 | P4HTM (0.38) | P4HTMCYP1A2HSP90AA1HSP90AB1BLM | |
| SCHEMBL8096944 | 0.87 | SMN1; SMN2 (0.39) | P4HTMCYP1A2HSP90AA1HSP90AB1BLM | |
| SCHEMBL8874936 | 0.87 | PTGS2 (0.46) | P4HTMSMN1; SMN2PTGS2KMT2AEGFR | |
| SCHEMBL8874675 | 0.83 | L3MBTL1 (0.43) | CYP1A2BLMSMN1; SMN2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620996-A | Sulfonamidocarbonyl pyridine-2-carboxesteramides and their pyridine-N-oxide compounds and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-04-15 | — | — | US | disclosed |