Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875242 | 0.96 | LIMK1 (0.39) | P4HTMALDH1A1KDM4ESMN1; SMN2PTGS2 | |
| SCHEMBL8875475 | 0.93 | P4HTM (0.39) | P4HTMALDH1A1SMN1; SMN2PTGS2KMT2A | |
| SCHEMBL8099328 | 0.88 | P4HTM (0.37) | P4HTMALDH1A1KDM4ESMN1; SMN2PTGS2 | |
| SCHEMBL8875238 | 0.87 | MEN1 (0.44) | P4HTMKMT2AMEN1 | |
| SCHEMBL8917617 | 0.86 | LIMK1 (0.42) | P4HTMALDH1A1KDM4EPTGS2LIMK1 | |
| SCHEMBL8874936 | 0.86 | PTGS2 (0.46) | P4HTMSMN1; SMN2PTGS2KMT2AEGFR | |
| SCHEMBL8875047 | 0.84 | SMN1; SMN2 (0.36) | P4HTMALDH1A1SMN1; SMN2PTGS2KMT2A | |
| SCHEMBL8916746 | 0.84 | EGLN1 (0.42) | P4HTMSMN1; SMN2PTGS2EGFRLIMK1 | |
| SCHEMBL8873580 | 0.83 | EGLN1 (0.41) | P4HTMSMN1; SMN2PTGS2KMT2AEGFR | |
| SCHEMBL8875237 | 0.83 | P4HTM (0.38) | P4HTMSMN1; SMN2PTGS2KMT2AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620996-A | Sulfonamidocarbonyl pyridine-2-carboxesteramides and their pyridine-N-oxide compounds and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-04-15 | — | — | US | disclosed |