Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 18/20 | 0.46 |
| ▸ | EGLN3 | Q9H6Z9 | 5/20 | 0.45 |
| ▸ | VEGFA | P15692 | 4/20 | 0.45 |
| ▸ | FLT1 | P17948 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8873580 | 0.89 | EGLN1 (0.41) | EGLN1EGLN3VEGFAFLT1LMNA | |
| SCHEMBL8916746 | 0.88 | EGLN1 (0.42) | EGLN1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL8768423 | 0.85 | LMNA (0.41) | LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL8917435 | 0.85 | LMNA (0.38) | EGLN1EGLN3VEGFAFLT1LMNA | |
| SCHEMBL8917617 | 0.80 | LIMK1 (0.42) | EGLN1 | |
| SCHEMBL8875237 | 0.80 | P4HTM (0.38) | EGLN1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL8916345 | 0.79 | EGLN1 (0.51) | EGLN1HTTSMN1; SMN2 | |
| SCHEMBL8917011 | 0.79 | LMNA (0.48) | EGLN1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8767162 | 0.78 | LMNA (0.40) | EGLN1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL8875475 | 0.78 | P4HTM (0.39) | LMNAHPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610172-A | Sulfonamidocarbonylpyridine-2-carboxamides and pyridine-n-oxides which are useful as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-11 | — | — | US | disclosed |