Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HPN | P05981 | 4/20 | 0.34 |
| ▸ | PLAU | P00749 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL887315 | 0.88 | TSHR (0.38) | METAP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL887371 | 0.75 | AGER (0.41) | POLBPLAUMEN1KMT2AAGER | |
| SCHEMBL887361 | 0.70 | HTR2A (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL15218689 | 0.65 | ALDH1A1 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9502275 | 0.64 | ALDH1A1 (0.49) | METAP2ALDH1A1GAAKCNH2TSHR | |
| SCHEMBL887320 | 0.64 | AGER (0.42) | POLBMEN1KMT2AAGERCNR2 | |
| SCHEMBL3280160 | 0.62 | POLB (0.54) | ALDH1A1GAATSHRCYP3A4POLB | |
| SCHEMBL887415 | 0.61 | GAA (0.50) | ALDH1A1GAATSHRCYP3A4POLB | |
| Cyclohexylglycyl SCHEMBL3568680 | 0.61 | ADORA3 (0.46) | METAP2ALDH1A1GAAKCNH2TSHR | |
| Cyclohexylglycyl SCHEMBL3574344 | 0.61 | ADORA3 (0.46) | METAP2ALDH1A1GAAKCNH2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7902207-B2 | Process for production of amines | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-03-08 | — | — | US | disclosed |
| US-20070142639-A1 | Process for production of amines | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142639-A1 | Process for production of amines | SMS, CCNT1, PEAK1 | METAP2 1622/4885PSEN1 358/4885PSEN2 580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.