Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875496 | 0.93 | ALDH1A1 (0.45) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL8917143 | 0.91 | LMNA (0.49) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL8089693 | 0.90 | ALDH1A1 (0.44) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL8875722 | 0.89 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL8096976 | 0.85 | ALDH1A1 (0.44) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL8915470 | 0.84 | LMNA (0.49) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL8868484 | 0.83 | ALDH1A1 (0.48) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL8868784 | 0.83 | P4HTM (0.51) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL8875576 | 0.83 | MAPT (0.49) | LMNAMAPTKMT2AMEN1CA12 | |
| SCHEMBL9136744 | 0.82 | ALDH1A1 (0.51) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620996-A | Sulfonamidocarbonyl pyridine-2-carboxesteramides and their pyridine-N-oxide compounds and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-04-15 | — | — | US | disclosed |