Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875722 | 0.93 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2MAPTNLRP3 | |
| SCHEMBL8875122 | 0.93 | ALDH1A1 (0.45) | ALDH1A1LMNASMN1; SMN2MAPTNLRP3 | |
| SCHEMBL8915470 | 0.91 | LMNA (0.49) | ALDH1A1LMNASMN1; SMN2MAPTNLRP3 | |
| SCHEMBL8096976 | 0.90 | ALDH1A1 (0.44) | ALDH1A1LMNASMN1; SMN2MAPTNLRP3 | |
| SCHEMBL8089693 | 0.85 | ALDH1A1 (0.44) | ALDH1A1LMNASMN1; SMN2MAPTNLRP3 | |
| SCHEMBL8097619 | 0.85 | ALDH1A1 (0.41) | ALDH1A1LMNASMN1; SMN2MAPTNLRP3 | |
| SCHEMBL8915243 | 0.84 | LMNA (0.45) | ALDH1A1LMNASMN1; SMN2MAPTNLRP3 | |
| SCHEMBL8917143 | 0.84 | LMNA (0.49) | ALDH1A1LMNASMN1; SMN2MAPTNLRP3 | |
| SCHEMBL8868484 | 0.83 | ALDH1A1 (0.48) | ALDH1A1LMNASMN1; SMN2MAPTNLRP3 | |
| SCHEMBL8868784 | 0.83 | P4HTM (0.51) | ALDH1A1LMNASMN1; SMN2MAPTNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620996-A | Sulfonamidocarbonyl pyridine-2-carboxesteramides and their pyridine-N-oxide compounds and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-04-15 | — | — | US | disclosed |