SCHEMBL887485

SCHEMBL887485

COc1ccc(C(OCCCCCCO)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC6A11 P48066 4/20 0.46
SLC6A1 P30531 2/20 0.46
KIF11 P52732 5/20 0.46
KCNH2 Q12809 1/20 0.46
TK2 O00142 4/20 0.41
MEN1 O00255 1/20 0.41
TP53 P04637 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
KMT2A Q03164 1/20 0.41
SLC6A12 P48065 1/20 0.41
SLC6A13 Q9NSD5 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6849984 1.00 SLC6A11 (0.46) SLC6A11SLC6A1KIF11KCNH2TK2
SCHEMBL27051202 1.00 SLC6A11 (0.46) SLC6A11SLC6A1KIF11KCNH2TK2
SCHEMBL13427508 1.00 SLC6A11 (0.46) SLC6A11SLC6A1KIF11KCNH2TK2
SCHEMBL1260569 1.00 SLC6A11 (0.46) SLC6A11SLC6A1KIF11KCNH2TK2
SCHEMBL8860350 0.98 SLC6A11 (0.47) SLC6A11SLC6A1KIF11KCNH2MEN1
SCHEMBL334143 0.94 SLC6A11 (0.48) SLC6A11SLC6A1KIF11KCNH2MEN1
SCHEMBL26415000 0.93 SLC6A11 (0.44) SLC6A11SLC6A1KIF11KCNH2MEN1
SCHEMBL8327519 0.92 KIF11 (0.42) SLC6A11SLC6A1KIF11KCNH2TK2
SCHEMBL19437634 0.90 SLC6A11 (0.43) SLC6A11SLC6A1KIF11KCNH2TK2
SCHEMBL20915040 0.90 SLC6A11 (0.43) SLC6A11SLC6A1KIF11KCNH2TK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250302995-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF SHIVALILA CHIKDU SHAKTI (US) 2025-10-02 US disclosed
EP-4522744-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF Wave Life Sciences Ltd. (SG) 2025-03-19 EP disclosed
CN-119452084-A Oligonucleotide compositions and methods thereof 波涛生命科学有限公司 2025-02-14 CN disclosed
US-20240218442-A1 METHODS FOR INDEXING SAMPLES AND SEQUENCING MULTIPLE POLYNUCLEOTIDE TEMPLATES ILLUMINA CAMBRIDGE LIMITED (GB) 2024-07-04 US disclosed
WO-2023220440-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2023-11-16 WO disclosed
US-9999866-B2 Preparation of templates for nucleic acid sequencing ILLUMINA CAMBRIDGE LIMITED (GB) 2018-06-19 US disclosed
EP-2749566-B1 SOLID-PHASE CARRIER FOR AMINATED OLIGONUCLEOTIDE AIST (JP) 2018-05-09 EP disclosed
US-9822134-B2 System for delivering therapeutic agents into living cells and cells nuclei SABAG-RFA LTD. (IL) 2017-11-21 US disclosed
US-9822134-B2 System for delivering therapeutic agents into living cells and cells nuclei SABAG-RFA LTD. (IL) 2017-11-21 US disclosed
US-20170145499-A1 METHODS FOR INDEXING SAMPLES AND SEQUENCING MULTIPLE POLYNUCLEOTIDE TEMPLATES ILLUMINA CAMBRIDGE LIMITED (US) 2017-05-25 US disclosed
US-20090233802-A1 Methods for indexing samples and sequencing multiple polynucleotide templates NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2009-09-17 US disclosed
US-20090118128-A1 Preparation of templates for nucleic acid sequencing ILLUMINA CAMBRIDGE LIMITED (GB) 2009-05-07 US disclosed
US-20090088327-A1 Method for sequencing a polynucleotide template SOLEXA LIMITED (GB) 2009-04-02 US disclosed
WO-2008093098-A2 METHODS FOR INDEXING SAMPLES AND SEQUENCING MULTIPLE NUCLEOTIDE TEMPLATES ILLUMINA CAMBRIDGE LIMITED (GB) 2008-08-07 WO disclosed
WO-2007010251-A2 PREPARATION OF TEMPLATES FOR NUCLEIC ACID SEQUENCING SOLEXA LIMITED (GB) 2007-01-25 WO disclosed
US-5912340-A FORMING STABLE HYBRID WITH DNA, RNA EPOCH PHARMACEUTICALS, INC. (US) 1999-06-15 US disclosed
US-5419966-A Solid support for synthesis of 3'-tailed oligonucleotides MICROPROBE CORPORATION (US) 1995-05-30 US disclosed
EP-0547142-A4 MICROPROBE CORP (US) 1995-01-18 EP disclosed
EP-0547142-A1 SOLID SUPPORT SYNTHESIS OF 3'-TAILED OLIGONUCLEOTIDES VIA A LINKING MOLECULE EPOCH PHARMACEUTICALS, INC. (US) 1993-06-23 EP disclosed
WO-1992003464-A1 SOLID SUPPORT SYNTHESIS OF 3'-TAILED OLIGONUCLEOTIDES VIA A LINKING MOLECULE MICROPROBE CORPORATION (US) 1992-03-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250302995-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF ADAR, NSUN2, RNGTT SLC6A11 4777/4885SLC6A1 4770/4885KIF11 3613/4885
US-20090118128-A1 Preparation of templates for nucleic acid sequencing RNGTT, POLRMT, POLM SLC6A11 4807/4885SLC6A1 4778/4885KIF11 1305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.