Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | VHL | P40337 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875741 | 0.91 | ALDH1A1 (0.38) | POLBKMT2AALDH1A1LMNAP2RX7 | |
| SCHEMBL8877111 | 0.88 | ALDH1A1 (0.37) | POLBKMT2AALDH1A1LMNAP2RX7 | |
| SCHEMBL8876139 | 0.85 | VHL (0.42) | POLBCYP1A2CYP3A4CYP2C19VHL | |
| SCHEMBL8877501 | 0.84 | MDM2 (0.39) | POLBAPOBEC3AAPOBEC3GKMT2AALDH1A1 | |
| SCHEMBL8877150 | 0.83 | POLB (0.39) | POLBAPOBEC3AAPOBEC3GKMT2AALDH1A1 | |
| SCHEMBL8317318 | 0.82 | POLB (0.35) | POLBCYP1A2CYP3A4CYP2C19VHL | |
| SCHEMBL8877689 | 0.82 | TSHR (0.42) | POLBVHLKMT2AALDH1A1LMNA | |
| SCHEMBL8876496 | 0.80 | KMT2A (0.40) | POLBVHLAPOBEC3AAPOBEC3GKMT2A | |
| SCHEMBL9727473 | 0.80 | FKBP1A (0.47) | POLBKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL9724044 | 0.80 | P2RX7 (0.36) | POLBKMT2AALDH1A1LMNAP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693663-A | PESTICIDES; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-02 | — | — | US | disclosed |
| US-5585384-A | 1-OXY-FUNCTIONAL GROUP-2-ALKYLARYL-3-OXO-PYRROLIZINES; INSECTICIDES; NEMATOCIDES; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| US-5288874-A | Insecticides, miticides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-22 | — | — | US | disclosed |