Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 12/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.39 |
| ▸ | MEN1 | O00255 | 8/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.39 |
| ▸ | S100B | P04271 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8393194 | 1.00 | KDR (0.47) | KDRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL887602 | 0.88 | MAPT (0.50) | KDRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9408530 | 0.88 | MAPT (0.38) | KDRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9408529 | 0.88 | MAPT (0.38) | KDRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11948808 | 0.84 | ALDH1A1 (0.41) | KDRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL13337935 | 0.84 | KDR (0.42) | KDRMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL11948809 | 0.83 | ALDH1A1 (0.46) | KDRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5047688 | 0.83 | KDR (0.39) | KDRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL14206916 | 0.83 | KDR (0.39) | KDRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11320251 | 0.82 | MAPT (0.42) | KDRMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067177-B2 | Amplification methods | EPOCH BIOSCIENCES, INC. (US) | 2011-11-29 | — | — | US | disclosed |
| US-7897736-B2 | Fluorescent quenching detecting reagents and methods | ELITECH HOLDING B.V. (NL) | 2011-03-01 | — | — | US | disclosed |
| US-7897736-B2 | Fluorescent quenching detecting reagents and methods | ELITECH HOLDING B.V. (NL) | 2011-03-01 | — | — | US | disclosed |
| US-20110027780-A1 | AMPLIFICATION METHODS | ELITECHGROUP MDX LLC | 2011-02-03 | — | — | US | disclosed |
| US-7759126-B2 | Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for amplification (or PCR) analysis | ELITECH HOLDING B.V. (NL) | 2010-07-20 | — | — | US | disclosed |
| US-20100174058-A1 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS | ELITECHGROUP, INC. | 2010-07-08 | — | — | US | disclosed |
| US-20100174058-A1 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS | ELITECHGROUP, INC. | 2010-07-08 | — | — | US | disclosed |
| US-7723038-B2 | Amplification methods | ELITECH HOLDING B.V. (NL) | 2010-05-25 | — | — | US | disclosed |
| US-7718374-B2 | Single nucleotide polymorphism analysis of highly polymorphic target sequences | ELITECH HOLDING B.V. (NL) | 2010-05-18 | — | — | US | disclosed |
| US-7662942-B2 | Oligonucleotide probes containing two labels useful in hybridization assays | Elitech Holdings, B.V. (NL) | 2010-02-16 | — | — | US | disclosed |
| US-7205105-B2 | Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for PCR analysis | EPOCH BIOSCIENCES, INC. (US) | 2007-04-17 | — | — | US | disclosed |
| US-20070003957-A1 | Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis | EPOCH BIOSCIENCES, INC. (US) | 2007-01-04 | — | — | US | disclosed |
| US-20070003957-A1 | Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis | EPOCH BIOSCIENCES, INC. (US) | 2007-01-04 | — | — | US | disclosed |
| US-RE36357-E | IMPROVED BRIGHTNESS OF SHADE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1999-10-26 | — | — | US | disclosed |
| EP-0399673-B1 | Thermal transfer printing | ZENECA LTD (GB) | 1994-09-07 | — | — | EP | disclosed |
| US-5091360-A | Using black dye mixture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-25 | — | — | US | disclosed |
| EP-0399673-A1 | Thermal transfer printing | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-11-28 | — | — | EP | disclosed |
| EP-0216483-B1 | THERMAL TRANSFER PRINTING | ZENECA LIMITED (GB) | 1990-04-11 | — | — | EP | disclosed |
| US-4764178-A | Thermal transfer printing: hetero-aromatic azo dye | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-16 | — | — | US | disclosed |
| EP-0216483-A1 | Thermal transfer printing | ZENECA LIMITED (GB) | 1987-04-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100174058-A1 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS | DDX5, DDX21, DCLRE1B | KDR 3386/4885MAPT 4706/4885ALDH1A1 2211/4885 |
| US-20070003957-A1 | Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis | RNGTT, DCLRE1B, CNBP | KDR 3951/4885MAPT 4694/4885ALDH1A1 3606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.