Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL887581 | 0.88 | KDR (0.47) | MAPTPOLBTDP1SMN1; SMN2MEN1 | |
| SCHEMBL8393194 | 0.88 | KDR (0.47) | MAPTPOLBTDP1SMN1; SMN2MEN1 | |
| SCHEMBL13337935 | 0.85 | KDR (0.42) | MAPTPOLBTDP1SMN1; SMN2MEN1 | |
| SCHEMBL8016440 | 0.83 | MAPT (0.55) | MAPTPOLBTDP1SMN1; SMN2MEN1 | |
| SCHEMBL1098887 | 0.83 | ALDH1A1 (0.44) | MAPTPOLBTDP1SMN1; SMN2MEN1 | |
| SCHEMBL1098885 | 0.83 | ALDH1A1 (0.44) | MAPTPOLBTDP1SMN1; SMN2MEN1 | |
| SCHEMBL13252803 | 0.81 | MEN1 (0.38) | MAPTPOLBTDP1MEN1KMT2A | |
| SCHEMBL17589107 | 0.80 | KDR (0.42) | MAPTPOLBTDP1SMN1; SMN2MEN1 | |
| SCHEMBL14470461 | 0.80 | MAPT (0.54) | MAPTPOLBTDP1SMN1; SMN2MEN1 | |
| SCHEMBL11058388 | 0.80 | ALDH1A1 (0.39) | MAPTPOLBTDP1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067177-B2 | Amplification methods | EPOCH BIOSCIENCES, INC. (US) | 2011-11-29 | — | — | US | disclosed |
| US-8067177-B2 | Amplification methods | EPOCH BIOSCIENCES, INC. (US) | 2011-11-29 | — | — | US | disclosed |
| US-7897736-B2 | Fluorescent quenching detecting reagents and methods | ELITECH HOLDING B.V. (NL) | 2011-03-01 | — | — | US | disclosed |
| US-7897736-B2 | Fluorescent quenching detecting reagents and methods | ELITECH HOLDING B.V. (NL) | 2011-03-01 | — | — | US | disclosed |
| US-20110027780-A1 | AMPLIFICATION METHODS | ELITECHGROUP MDX LLC | 2011-02-03 | — | — | US | disclosed |
| US-20110027780-A1 | AMPLIFICATION METHODS | ELITECHGROUP MDX LLC | 2011-02-03 | — | — | US | disclosed |
| US-20100174058-A1 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS | ELITECHGROUP, INC. | 2010-07-08 | — | — | US | disclosed |
| US-20100174058-A1 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS | ELITECHGROUP, INC. | 2010-07-08 | — | — | US | disclosed |
| US-7723038-B2 | Amplification methods | ELITECH HOLDING B.V. (NL) | 2010-05-25 | — | — | US | disclosed |
| US-7723038-B2 | Amplification methods | ELITECH HOLDING B.V. (NL) | 2010-05-25 | — | — | US | disclosed |
| US-7485442-B2 | Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis | EPOCH BIOSCIENCES, INC. (US) | 2009-02-03 | — | — | US | disclosed |
| US-7485442-B2 | Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis | EPOCH BIOSCIENCES, INC. (US) | 2009-02-03 | — | — | US | disclosed |
| US-20080248474-A1 | AMPLIFICATION METHODS | EPOCH BIOSCIENCES, INC (US) | 2008-10-09 | — | — | US | disclosed |
| US-20080248474-A1 | AMPLIFICATION METHODS | EPOCH BIOSCIENCES, INC (US) | 2008-10-09 | — | — | US | disclosed |
| US-7319022-B1 | Amplification and monitoring of oligonucleotide amplification in which a primer has an overlap with one or more bases of a detection probe | EPOCH BIOSCIENCES, INC. (US) | 2008-01-15 | — | — | US | disclosed |
| US-7319022-B1 | Amplification and monitoring of oligonucleotide amplification in which a primer has an overlap with one or more bases of a detection probe | EPOCH BIOSCIENCES, INC. (US) | 2008-01-15 | — | — | US | disclosed |
| US-7205105-B2 | Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for PCR analysis | EPOCH BIOSCIENCES, INC. (US) | 2007-04-17 | — | — | US | disclosed |
| US-7205105-B2 | Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for PCR analysis | EPOCH BIOSCIENCES, INC. (US) | 2007-04-17 | — | — | US | disclosed |
| US-20070003957-A1 | Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis | EPOCH BIOSCIENCES, INC. (US) | 2007-01-04 | — | — | US | disclosed |
| US-20070003957-A1 | Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis | EPOCH BIOSCIENCES, INC. (US) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100174058-A1 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS | DDX5, DDX21, DCLRE1B | MAPT 4706/4885POLB 387/4885TDP1 487/4885 |
| US-20070003957-A1 | Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis | RNGTT, DCLRE1B, CNBP | MAPT 4694/4885POLB 7/4885TDP1 280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.