Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8874054 | 0.83 | ALDH1A1 (0.41) | ALDH1A1LMNAHSP90AA1HSP90AB1HIF1A | |
| SCHEMBL8876294 | 0.76 | HSP90AA1 (0.39) | ALDH1A1LMNAHSP90AA1HSP90AB1 | |
| SCHEMBL8876030 | 0.75 | HSP90AA1 (0.37) | HSP90AA1HSP90AB1 | |
| SCHEMBL8874887 | 0.72 | ALDH1A1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL31382210 | 0.71 | SMN1; SMN2 (0.39) | ALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL23174841 | 0.65 | MAPT (0.37) | ALDH1A1LMNAHSP90AA1HSP90AB1 | |
| SCHEMBL27909594 | 0.63 | LMNA (0.40) | ALDH1A1LMNA | |
| SCHEMBL16389913 | 0.62 | LMNA (0.40) | ALDH1A1LMNAHIF1AEPAS1 | |
| SCHEMBL9799545 | 0.62 | KMT2A (0.50) | ALDH1A1LMNA | |
| SCHEMBL9608808 | 0.61 | PABPC1 (0.55) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643929-A | TREATMENT OF PICORNAVIRAL OR RHINOVIRUS AND CHEMICAL INTERMEDIATES | SANOFI WINTHROP, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5464848-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1995-11-07 | — | — | US | disclosed |