Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GABRE | P78334 | 1/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.31 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.31 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.31 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23611618 | 0.72 | NOTUM (0.33) | ALDH1A1DAO | |
| SCHEMBL28466306 | 0.70 | ALDH1A1 (0.42) | ALDH1A1GABRB2GABRA2 | |
| SCHEMBL5960570 | 0.65 | GABRA1 (0.33) | GABRA1GABRB2 | |
| SCHEMBL30599221 | 0.65 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL3674782 | 0.64 | L3MBTL1 (0.40) | ALDH1A1L3MBTL1 | |
| Bicarbonate SCHEMBL14635340 | 0.61 | GABRA1 (0.55) | ALDH1A1GABRA1GABRB2L3MBTL1 | |
| Bicarbonate SCHEMBL29051241 | 0.61 | GABRA1 (0.55) | ALDH1A1GABRA1GABRB2L3MBTL1 | |
| Acetic Acid SCHEMBL1724578 | 0.59 | GABRA1 (0.52) | ALDH1A1GABRA1GABRB2L3MBTL1 | |
| SCHEMBL4116012 | 0.59 | GABRP (0.50) | ALDH1A1GABRA1GABRB2GABRPGABRD | |
| SCHEMBL2334997 | 0.59 | GABRP (0.55) | ALDH1A1GABRA1GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672717-A | ANTITUMOR AGENTS TREATING CANCER | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1997-09-30 | — | — | US | disclosed |
| US-5554764-A | DIPYRROMETHANES ARE CLAIMED. | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1996-09-10 | — | — | US | disclosed |
| US-5446166-A | Reacting isocyanoacetate with prophosphatrane and acyl halide or acid anhydride | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1995-08-29 | — | — | US | disclosed |
| US-5367084-A | Preparation of pyrrol and oxazole compounds: formation of porphyrins and c-acyl-α-amino acid esters therefrom | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1994-11-22 | — | — | US | disclosed |