Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26929161 | 0.80 | TSHR (0.48) | TSHRACHEPPARDPOLBTP53 | |
| Potassium Ion SCHEMBL2470578 | 0.80 | — | — | |
| SCHEMBL2471601 | 0.79 | PPARD (0.39) | GAATSHRACHEPPARDTP53 | |
| SCHEMBL887692 | 0.78 | PPARD (0.38) | GAATSHRACHEPPARDTP53 | |
| SCHEMBL5349960 | 0.78 | — | — | |
| SCHEMBL1006223 | 0.75 | — | — | |
| SCHEMBL11565386 | 0.75 | TSHR (0.53) | TSHRACHEPPARDTP53TDP1 | |
| Lithium Ion SCHEMBL20543352 | 0.75 | — | — | |
| SCHEMBL11093609 | 0.75 | TSHR (0.53) | TSHRACHEPPARDTP53TDP1 | |
| Silver SCHEMBL4144403 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2201827-B1 | NEGATIVE IMAGING METHOD FOR PROVIDING A PATTERNED METAL LAYER HAVING HIGH CONDUCTIVITY | DU PONT (US) | 2014-04-23 | — | — | EP | disclosed |
| US-8440383-B2 | Metal compositions, thermal imaging donors and patterned multilayer compositions derived therefrom | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-14 | — | — | US | disclosed |
| EP-2041626-B1 | A PROCESS FOR ENHANCING THE RESOLUTION OF A THERMALLY TRANSFERRED PATTERN | DU PONT (US) | 2013-04-10 | — | — | EP | disclosed |
| US-8377622-B2 | Thermally imageable dielectric layers, thermal transfer donors and receivers | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-02-19 | — | — | US | disclosed |
| US-8308886-B2 | Donor elements and processes for thermal transfer of nanoparticle layers | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-11-13 | — | — | US | disclosed |
| US-20120251802-A1 | THERMALLY IMAGEABLE DIELECTRIC LAYERS, THERMAL TRANSFER DONORS AND RECEIVERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-10-04 | — | — | US | disclosed |
| EP-2482355-A1 | Thin film transistor comprising novel conductor and dielectric compositions | E. I. du Pont de Nemours and Company (US) | 2012-08-01 | — | — | EP | disclosed |
| EP-2482354-A1 | Thin film transistor comprising novel conductor and dielectric compositions | E. I. du Pont de Nemours and Company (US) | 2012-08-01 | — | — | EP | disclosed |
| CN-101569245-B | Metal compositions, donors and patterned multilayer compositions, shield and sensor | DU PONT | 2012-01-11 | — | — | CN | disclosed |
| US-8062824-B2 | Thermally imageable dielectric layers, thermal transfer donors and receivers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-11-22 | — | — | US | disclosed |
| WO-2008010983-A2 | THIN FILM TRANSISTOR COMPRISING NOVEL CONDUCTOR AND DIELECTRIC COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-01-24 | — | — | WO | disclosed |
| WO-2008010982-A2 | THERMALLY IMAGEABLE DIELECTRIC LAYERS, THERMAL TRANSFER DONORS AND RECEIVERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-01-24 | — | — | WO | disclosed |
| WO-2008010981-A2 | A PROCESS FOR ENHANCING THE RESOLUTION OF A THERMALLY TRANSFERRED PATTERN | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-01-24 | — | — | WO | disclosed |
| US-20080012163-A1 | Process for enhancing the resolution of a thermally transferred pattern | E. I. DU PONT DE NEMOURS AND COMPANY | 2008-01-17 | — | — | US | disclosed |
| US-20080012006-A1 | Thin film transistor comprising novel conductor and dielectric compositions | E. I. DU PONT DE NEMOURS AND COMPANY | 2008-01-17 | — | — | US | disclosed |
| US-20080014528-A1 | Metal compositions, thermal imaging donors and patterned multilayer compositions derived therefrom | E. I. DU PONT DE NEMOURS AND COMPANY | 2008-01-17 | — | — | US | disclosed |
| EP-1805035-A1 | COMPOSITE FILM SUITABLE AS A DONOR SUPPORT IN A RADIATION-INDUCED THERMAL TRANSFER IMAGING PROCESS | Dupont Teijin Films U.S. Limited Partnership (US) | 2007-07-11 | — | — | EP | disclosed |
| EP-1802471-A1 | DONOR ELEMENT FOR RADIATION-INDUCED THERMAL TRANSFER | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006043072-A1 | COMPOSITE FILM SUITABLE AS A DONOR SUPPORT IN A RADIATION-INDUCED THERMAL TRANSFER IMAGING PROCESS | DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) | 2006-04-27 | — | — | WO | disclosed |
| WO-2006045083-A1 | DONOR ELEMENT FOR RADIATION-INDUCED THERMAL TRANSFER | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-04-27 | — | — | WO | disclosed |