Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 6/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 3/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007278 | 0.85 | SNCA (0.66) | SNCAKMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL8941280 | 0.84 | SNCA (0.82) | SNCAKMT2AMEN1MAPTPOLB | |
| SCHEMBL239724 | 0.81 | SNCA (1.00) | SNCAKMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL30769632 | 0.81 | SNCA (1.00) | SNCAKMT2AMEN1L3MBTL1MAPT | |
| Phenothiazine SCHEMBL27788701 | 0.80 | SNCA (0.81) | SNCAKMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL6298018 | 0.78 | KMT2A (1.00) | SNCAKMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL8988 | 0.77 | L3MBTL1 (1.00) | SNCAKMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL8878671 | 0.77 | L3MBTL1 (0.68) | SNCAKMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL1567426 | 0.77 | L3MBTL1 (0.68) | SNCAKMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL31098239 | 0.77 | L3MBTL1 (0.68) | SNCAKMT2AMEN1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607929-A | Antiviral dibenzothiazepinone derivatives | GLAXO WELLCOME INC. (US) | 1997-03-04 | — | — | US | disclosed |
| US-5589474-A | Dibenzothiazepinthione as antiviral agents | GLAXO WELLCOME INC. (US) | 1996-12-31 | — | — | US | disclosed |
| EP-0583317-A1 | DIBENZOTHIAZEPINTHIONE AS ANTIVIRAL AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-02-23 | — | — | EP | disclosed |
| WO-1992019607-A1 | DIBENZOTHIAZEPINTHIONE AS ANTIVIRAL AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-11-12 | — | — | WO | disclosed |