Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.45 |
| ▸ | ALPL | P05186 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2650875 | 0.78 | IDO1 (0.42) | NPC1RAB9A | |
| SCHEMBL3597375 | 0.73 | RAB9A (0.41) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL16720064 | 0.71 | KMO (0.45) | KMOMEN1KMT2ACYP3A4MAOB | |
| SCHEMBL2752569 | 0.71 | KMO (0.40) | KMOALPLMEN1NPC1RAB9A | |
| SCHEMBL19072696 | 0.69 | KMO (0.54) | KMOALPLMEN1NPC1RAB9A | |
| SCHEMBL29445848 | 0.69 | KMO (0.54) | KMOALPLMEN1NPC1RAB9A | |
| SCHEMBL1444770 | 0.69 | KMO (0.51) | KMOALPLMEN1NPC1RAB9A | |
| SCHEMBL9135463 | 0.68 | ALDH1A1 (0.52) | KMOMEN1KMT2A | |
| SCHEMBL1537654 | 0.68 | ALPL (0.40) | KMOALPLMEN1NPC1RAB9A | |
| SCHEMBL2753016 | 0.68 | ALPL (0.40) | KMOALPLF2RL3TP53MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5604182-A | EXHIBIT ANTHELMINTIC, ACARICIDAL AND INSECTICIDAL ACTIVITIES | SANKYO COMPANY LIMITED (JP) | 1997-02-18 | — | — | US | disclosed |
| US-5346918-A | Anthelmintics, acaridices, insecticides | SANKYO COMPANY LIMITED (JP) | 1994-09-13 | — | — | US | disclosed |