Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15477525 | 0.79 | KMO (0.45) | KMOIDO1MAOBPIM1NOTUM | |
| SCHEMBL11107619 | 0.79 | METAP2 (0.45) | — | |
| SCHEMBL16720101 | 0.79 | HSD17B1 (0.52) | CYP17A1CYP3A4CYP11B1CYP11B2ESR2 | |
| SCHEMBL557899 | 0.77 | KMT2A (0.41) | IDO1NISCHMEN1KMT2AALDH1A1 | |
| SCHEMBL3654046 | 0.71 | CYP1A2 (0.47) | KDM4ENISCHMEN1MAPTKMT2A | |
| SCHEMBL8879424 | 0.71 | KMO (0.45) | KMOMEN1KMT2ACYP3A4MAOB | |
| SCHEMBL11108637 | 0.71 | MAPT (0.47) | KDM4EMAPTALDH1A1CYP3A4CYP11B1 | |
| SCHEMBL989535 | 0.70 | CYP2A6 (0.52) | KDM4ENISCHMAPTALDH1A1CYP3A4 | |
| SCHEMBL29470232 | 0.70 | MEN1 (0.58) | KMOIDO1KDM4EMEN1MAPT | |
| SCHEMBL1897911 | 0.69 | TAAR1 (0.48) | IDO1KDM4ENISCHMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |