Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22922181 | 0.90 | CYP4F2 (0.59) | CYP4F2CYP4A11IDO1F2RL1ADRB2 | |
| SCHEMBL27700759 | 0.89 | TSHR (0.48) | CYP4F2CYP4A11EPHX2ALDH1A1LMNA | |
| SCHEMBL1483117 | 0.89 | CYP4F2 (0.50) | CYP4F2CYP4A11IDO1F2RL1ADRB2 | |
| SCHEMBL9670477 | 0.86 | THRA (0.53) | CYP4F2CYP4A11IDO1F2RL1ADRB2 | |
| SCHEMBL8158284 | 0.85 | CYP4F2 (0.70) | CYP4F2CYP4A11ALDH1A1LMNAMAPT | |
| SCHEMBL516422 | 0.85 | IDO1 (0.65) | CYP4F2CYP4A11IDO1F2RL1ADRB2 | |
| SCHEMBL28549048 | 0.83 | ADRB2 (0.54) | F2RL1ADRB2ADRB1ALDH1A1LMNA | |
| SCHEMBL10583619 | 0.83 | TSHR (0.50) | CYP4F2CYP4A11F2RL1EPHX2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL16062033 | 0.83 | IDO1 (0.63) | CYP4F2CYP4A11IDO1F2RL1ADRB2 | |
| SCHEMBL1410420 | 0.82 | CYP4A11 (0.56) | CYP4F2CYP4A11IDO1F2RL1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624948-A | TREATMENT OF BRONCHIAL ASTHMA | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0699668-A1 | 1-(2-BENZIMIDAZOLYL)-1,5-DIAZACYCLOOCTANE DERIVATIVE | Kissei Pharmaceutical Co., Ltd. (JP) | 1996-03-06 | — | — | EP | disclosed |