Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 10/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.45 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.45 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9391202 | 0.81 | GSTO1 (0.55) | GSTO1ATAD2CYP3A4RAB9AMEN1 | |
| SCHEMBL8877679 | 0.74 | TSHR (0.49) | GSTO1KDM4ETSHRSMN1; SMN2KCNQ3 | |
| Isobutane SCHEMBL9369767 | 0.73 | GSTO1 (0.44) | GSTO1KDM4ETSHRCYP3A4MEN1 | |
| SCHEMBL9427582 | 0.72 | ALDH1A1 (0.51) | GSTO1KDM4ETSHRATAD2CYP3A4 | |
| SCHEMBL10347962 | 0.71 | TSHR (0.55) | KDM4ETSHRSMN1; SMN2CYP3A4RAB9A | |
| SCHEMBL9633422 | 0.71 | CYP3A4 (0.51) | KDM4ETSHRSMN1; SMN2CYP3A4RAB9A | |
| SCHEMBL9427381 | 0.70 | NPC1 (0.64) | KDM4ETSHRGAASMN1; SMN2CYP3A4 | |
| SCHEMBL10522018 | 0.70 | CYP3A4 (0.48) | GSTO1TSHRATAD2SMN1; SMN2CYP3A4 | |
| SCHEMBL9369763 | 0.70 | TSHR (0.45) | GSTO1KDM4ETSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL11777206 | 0.69 | TDP1 (0.45) | KDM4EATAD2SMN1; SMN2KCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631209-A | ALGICIDES | ROHM AND HAAS COMPANY (US) | 1997-05-20 | — | — | US | disclosed |
| US-5502027-A | ALGICIDES | ROHM AND HAAS COMPANY (US) | 1996-03-26 | — | — | US | disclosed |
| EP-0415642-B1 | Glutarimides | ROHM & HAAS (US) | 1995-12-06 | — | — | EP | disclosed |
| US-5393735-A | N-(halo-oxy-)phenyl substituted cyclic imides | ROHM AND HAAS COMPANY (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0415642-A1 | Glutarimides | ROHM AND HAAS COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |