Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10617845 | 0.77 | MEN1 (0.43) | GSTO1TSHRKDM4ECYP3A4MEN1 | |
| SCHEMBL9369763 | 0.77 | TSHR (0.45) | GSTO1TSHRKDM4ECYP3A4MEN1 | |
| SCHEMBL8879957 | 0.73 | GSTO1 (0.54) | GSTO1TSHRKDM4ECYP3A4MEN1 | |
| SCHEMBL9631086 | 0.72 | STK39 (0.48) | CYP3A4KMT2AGRM4 | |
| SCHEMBL9391202 | 0.72 | GSTO1 (0.55) | GSTO1CYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL9427582 | 0.71 | ALDH1A1 (0.51) | GSTO1TSHRKDM4ECYP3A4MEN1 | |
| SCHEMBL9633353 | 0.71 | PNLIP (0.46) | CYP3A4MEN1KMT2AALDH1A1GRM4 | |
| SCHEMBL9633422 | 0.70 | CYP3A4 (0.51) | TSHRKDM4ECYP3A4MEN1KMT2A | |
| SCHEMBL10347962 | 0.70 | TSHR (0.55) | TSHRKDM4ECYP3A4MEN1KMT2A | |
| SCHEMBL8877679 | 0.70 | TSHR (0.49) | GSTO1TSHRKDM4ECYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415641-B1 | Substituted glutaramic acids and derivatives | ROHM & HAAS (US) | 1994-01-19 | — | — | EP | disclosed |
| US-5238908-A | HERBICIDAL GLUTARAMIC ACIDS AND DERIVATIVES | ROHM AND HAAS COMPANY (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0415641-A1 | Substituted glutaramic acids and derivatives | ROHM AND HAAS COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |