Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9369763 | 0.80 | TSHR (0.45) | TSHRKDM4ECYP3A4ALDH1A1MEN1 | |
| SCHEMBL10347962 | 0.76 | TSHR (0.55) | TSHRKDM4ECYP3A4MEN1KMT2A | |
| SCHEMBL8879957 | 0.74 | GSTO1 (0.54) | TSHRKDM4ECYP3A4KCNQ3KCNQ2 | |
| SCHEMBL9633422 | 0.73 | CYP3A4 (0.51) | TSHRKDM4ECYP3A4ALDH1A1MEN1 | |
| SCHEMBL9427381 | 0.72 | NPC1 (0.64) | TSHRKDM4ECYP3A4ALDH1A1MEN1 | |
| Isobutane SCHEMBL9369767 | 0.70 | GSTO1 (0.44) | TSHRKDM4ECYP3A4ALDH1A1MEN1 | |
| SCHEMBL10617845 | 0.69 | MEN1 (0.43) | TSHRKDM4ECYP3A4ALDH1A1MEN1 | |
| SCHEMBL9391202 | 0.69 | GSTO1 (0.55) | CYP3A4ALDH1A1MEN1KMT2AGSTO1 | |
| SCHEMBL9427582 | 0.69 | ALDH1A1 (0.51) | TSHRKDM4ECYP3A4ALDH1A1MEN1 | |
| SCHEMBL8876963 | 0.68 | KMT2A (0.63) | CYP3A4ALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631209-A | ALGICIDES | ROHM AND HAAS COMPANY (US) | 1997-05-20 | — | — | US | disclosed |
| US-5502027-A | ALGICIDES | ROHM AND HAAS COMPANY (US) | 1996-03-26 | — | — | US | disclosed |
| EP-0415642-B1 | Glutarimides | ROHM & HAAS (US) | 1995-12-06 | — | — | EP | disclosed |
| US-5393735-A | N-(halo-oxy-)phenyl substituted cyclic imides | ROHM AND HAAS COMPANY (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0415641-B1 | Substituted glutaramic acids and derivatives | ROHM & HAAS (US) | 1994-01-19 | — | — | EP | disclosed |
| US-5238908-A | HERBICIDAL GLUTARAMIC ACIDS AND DERIVATIVES | ROHM AND HAAS COMPANY (US) | 1993-08-24 | — | — | US | disclosed |
| CN-1049846-A | Glutarimide with weeding activity | ROHM & HAAS (US) | 1991-03-13 | — | — | CN | disclosed |
| EP-0415641-A1 | Substituted glutaramic acids and derivatives | ROHM AND HAAS COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |
| EP-0415642-A1 | Glutarimides | ROHM AND HAAS COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |