Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 4/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8565075 | 0.88 | DRD4 (0.53) | HTR7ALDH1A1KDM4EKMT2AHTR1A | |
| SCHEMBL8565549 | 0.87 | MAPK1 (0.60) | ALDH1A1KDM4EKMT2AHTR1AHTR2C | |
| SCHEMBL8564672 | 0.82 | HTR1A (0.53) | HTR7HTR1AHTR2CDRD4SIGMAR1 | |
| SCHEMBL8570798 | 0.78 | DRD2 (0.50) | ALDH1A1KDM4EKMT2AALOX15TSHR | |
| SCHEMBL8566284 | 0.78 | DRD4 (0.54) | ALDH1A1HTR1AHTR2CDRD4DRD2 | |
| SCHEMBL8571687 | 0.77 | HTR1A (0.49) | KDM4EHTR1AHTR2CMAPK1DRD4 | |
| SCHEMBL8570291 | 0.76 | SLC2A1 (0.43) | ALDH1A1KMT2AHTR1AALOX15MEN1 | |
| SCHEMBL8569105 | 0.74 | DRD2 (0.52) | HTR1AHTR2CDRD4DRD2DRD3 | |
| SCHEMBL8571302 | 0.74 | ALDH1A1 (0.58) | ALDH1A1KDM4EKMT2AHTR1AHTR2C | |
| SCHEMBL8567130 | 0.74 | HTR1A (0.52) | KDM4EHTR1AHTR2CMAPK1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599812-A | ANTISEROTONINE AGENTS | ADIR ET COMPAGNIE (FR) | 1997-02-04 | — | — | US | disclosed |