Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8878706 | 0.82 | — | — | |
| SCHEMBL8878929 | 0.74 | — | — | |
| SCHEMBL8879355 | 0.69 | PKM (0.33) | MAPTTSHRPKM | |
| SCHEMBL9007307 | 0.69 | — | — | |
| SCHEMBL11880274 | 0.65 | GPR3 (0.43) | MAPTTSHRPKM | |
| SCHEMBL8880090 | 0.61 | ATM (0.31) | — | |
| SCHEMBL8879372 | 0.60 | HSD17B10 (0.47) | MAPTTSHRPKM | |
| SCHEMBL8258013 | 0.59 | PKM (0.49) | TSHRPKM | |
| SCHEMBL8877757 | 0.59 | CES1 (0.30) | — | |
| SCHEMBL13239917 | 0.57 | ALDH1A1 (0.36) | MAPTTSHRPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607929-A | Antiviral dibenzothiazepinone derivatives | GLAXO WELLCOME INC. (US) | 1997-03-04 | — | — | US | claimed |
| EP-0583288-A1 | ANTIVIZAL DIBENZOTHIAZEPINONE DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-02-23 | — | — | EP | claimed |
| WO-1992019277-A1 | ANTIVIRAL DIBENZOTHIAZEPINONE DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-11-12 | — | — | WO | claimed |
| US-5607929-A | Antiviral dibenzothiazepinone derivatives | GLAXO WELLCOME INC. (US) | 1997-03-04 | — | — | US | disclosed |