Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21808019 | 0.75 | — | — | |
| SCHEMBL5510055 | 0.70 | — | — | |
| SCHEMBL8882005 | 0.70 | — | — | |
| SCHEMBL5321800 | 0.67 | TNF (0.34) | — | |
| SCHEMBL8880934 | 0.67 | KDM4E (0.33) | — | |
| SCHEMBL350376 | 0.65 | — | — | |
| SCHEMBL526181 | 0.63 | ALDH1A1 (0.35) | — | |
| SCHEMBL9340535 | 0.62 | EGLN2 (0.40) | — | |
| SCHEMBL5206274 | 0.62 | TRPV4 (0.32) | — | |
| SCHEMBL2597730 | 0.61 | TRPV4 (0.37) | CUL4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5604225-A | DIETETICS; OBESITY | DR. KARL THOMAE GMBH (DE) | 1997-02-18 | — | — | US | disclosed |
| US-5457205-A | Substituted thiazoles useful for treatment of diabetes | DR. KARL THOMAE GMBH (DE) | 1995-10-10 | — | — | US | disclosed |
| US-5219852-A | Hypoglycemic agents, treatment of diabetes and obesity | DR. KARL THOMAE GMBH (DE) | 1993-06-15 | — | — | US | disclosed |
| US-4886814-A | LOWER BLOOD SUGAR | DR. KARL THOMAS GMBH (DE) | 1989-12-12 | — | — | US | disclosed |