Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MMEL1 | Q495T6 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CCKBR | P32239 | 2/20 | 0.33 |
| ▸ | CCKAR | P32238 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9228580 | 1.00 | ALDH1A1 (0.35) | ALDH1A1LMNAMMEL1BACE1MEN1 | |
| SCHEMBL9230692 | 0.84 | MEN1 (0.38) | ALDH1A1LMNABACE1MEN1KMT2A | |
| SCHEMBL8883034 | 0.84 | MEN1 (0.38) | ALDH1A1LMNABACE1MEN1KMT2A | |
| SCHEMBL9228775 | 0.84 | MMEL1 (0.36) | ALDH1A1LMNAMMEL1BACE1MEN1 | |
| SCHEMBL8882317 | 0.84 | MMEL1 (0.36) | ALDH1A1LMNAMMEL1BACE1MEN1 | |
| SCHEMBL8881756 | 0.83 | ALDH1A1 (0.36) | ALDH1A1LMNABACE1MEN1KMT2A | |
| SCHEMBL9230328 | 0.73 | ALDH1A1 (0.38) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9226675 | 0.72 | ALDH1A1 (0.38) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8882015 | 0.68 | ACE (0.39) | — | |
| SCHEMBL19911084 | 0.67 | TSHR (0.47) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679671-A | ANGIOTENSIN 1-CONVERTING ENZYME INHIBITOR, VASOPRESSIN ANTAGONISM AND ATRIAL NAUTRIURETIC PEPTIDE HYDROLASE INHIBITOR | EISAI CO., LTD. (JP) | 1997-10-21 | — | — | US | disclosed |