Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9228775 | 0.90 | MMEL1 (0.36) | ALDH1A1LMNAMEN1KMT2AHRH4 | |
| SCHEMBL8882317 | 0.90 | MMEL1 (0.36) | ALDH1A1LMNAMEN1KMT2AHRH4 | |
| SCHEMBL9226675 | 0.84 | ALDH1A1 (0.38) | ALDH1A1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL8883034 | 0.78 | MEN1 (0.38) | ALDH1A1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL9230692 | 0.78 | MEN1 (0.38) | ALDH1A1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL7439947 | 0.77 | ACE (0.59) | ABCB11ACEAGTR2PDE3ATDP1 | |
| SCHEMBL7439940 | 0.77 | ACE (0.59) | ABCB11ACEAGTR2PDE3ATDP1 | |
| SCHEMBL8883149 | 0.74 | ACE (0.56) | ACE | |
| SCHEMBL9228580 | 0.73 | ALDH1A1 (0.35) | ALDH1A1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL8884010 | 0.73 | ALDH1A1 (0.35) | ALDH1A1LMNAMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671172-A1 | AMINO ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-09-13 | — | — | EP | disclosed |