Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CCKBR | P32239 | 2/20 | 0.34 |
| ▸ | CCKAR | P32238 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ITGAM | P11215 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8883034 | 1.00 | MEN1 (0.38) | MEN1KMT2AALDH1A1LMNABACE1 | |
| SCHEMBL8882317 | 0.88 | MMEL1 (0.36) | MEN1KMT2AALDH1A1LMNABACE1 | |
| SCHEMBL9228775 | 0.88 | MMEL1 (0.36) | MEN1KMT2AALDH1A1LMNABACE1 | |
| SCHEMBL8884010 | 0.84 | ALDH1A1 (0.35) | MEN1KMT2AALDH1A1LMNABACE1 | |
| SCHEMBL9228580 | 0.84 | ALDH1A1 (0.35) | MEN1KMT2AALDH1A1LMNABACE1 | |
| SCHEMBL9226675 | 0.83 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1LMNARXFP1 | |
| SCHEMBL8881756 | 0.81 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1LMNABACE1 | |
| SCHEMBL9230328 | 0.78 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8882015 | 0.76 | ACE (0.39) | — | |
| SCHEMBL9230696 | 0.73 | CCKBR (0.39) | MEN1KMT2AALDH1A1LMNACCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671172-A1 | AMINO ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-09-13 | — | — | EP | disclosed |