Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.53 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.53 |
| ▸ | PPIA | P62937 | 1/20 | 0.49 |
| ▸ | KDM5A | P29375 | 1/20 | 0.49 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8883987 | 0.86 | KMT2A (0.56) | NR4A2PPIALMNAL3MBTL1MEN1 | |
| SCHEMBL30848623 | 0.84 | LTA4H (0.58) | SGMS2PPIA | |
| SCHEMBL2426791 | 0.84 | LTA4H (0.58) | SGMS2PPIA | |
| SCHEMBL8882076 | 0.84 | RXRA (0.56) | NR4A2MRGPRX4SGMS2PPIAKDM5A | |
| SCHEMBL8881801 | 0.83 | NR4A2 (0.58) | NR4A2MRGPRX4PPIAL3MBTL1MAOB | |
| Hydrochloric Acid SCHEMBL10705444 | 0.83 | LTA4H (0.57) | SGMS2PPIA | |
| SCHEMBL8785130 | 0.82 | MRGPRX4 (0.55) | MRGPRX4SGMS2ALKBH1MEN1KMT2A | |
| SCHEMBL27436417 | 0.81 | MRGPRX4 (0.53) | NR4A2MRGPRX4SGMS2KDM5AKDM5B | |
| SCHEMBL8883121 | 0.81 | MRGPRX4 (0.54) | NR4A2MRGPRX4LMNAKMT2A | |
| SCHEMBL8881484 | 0.79 | HTR1A (0.56) | SGMS2PPIALMNALRRK2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658933-A | Substituted heterocyclic carboxamide esters, their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-08-19 | — | — | US | disclosed |