Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.36 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.36 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8883687 | 0.82 | LCK (0.42) | MAPTKDM4EMEN1KMT2ACYP3A4 | |
| SCHEMBL8884241 | 0.80 | NQO2 (0.41) | NQO2MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2432823 | 0.80 | CREB1 (0.48) | MAPTKDM4ELMNAPOLBMEN1 | |
| SCHEMBL8885519 | 0.75 | GABRP (0.47) | NQO2MAPTKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL4082541 | 0.66 | MGLL (0.72) | MAPTKDM4EPOLB | |
| SCHEMBL30164935 | 0.66 | MGLL (0.72) | MAPTKDM4EPOLB | |
| SCHEMBL13680547 | 0.65 | CNR1 (0.61) | MEN1KMT2AHSD17B10AKT2 | |
| SCHEMBL3690365 | 0.65 | MAPT (0.59) | TOP1MAPTLMNAMEN1KMT2A | |
| SCHEMBL8642110 | 0.65 | CNR1 (0.64) | KDM4ELMNAPOLBMEN1KMT2A | |
| SCHEMBL3030393 | 0.65 | CA12 (0.44) | MAPTKDM4ELMNAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696110-A | ANTIULCER AGENTS | MERCK, SHARP & DOHME, LTD. (GB) | 1997-12-09 | — | — | US | disclosed |