Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8886818 | 1.00 | LMNA (0.44) | LMNATSHRALDH1A1MITFMAPT | |
| SCHEMBL27859227 | 0.85 | ALDH1A1 (0.43) | LMNATSHRALDH1A1MAPTKDM4E | |
| SCHEMBL17629550 | 0.81 | HMGB1 (0.54) | LMNAALDH1A1KDM4EHSD17B10GABRA1 | |
| SCHEMBL8887180 | 0.81 | HMGB1 (0.54) | LMNAALDH1A1KDM4EHSD17B10GABRA1 | |
| SCHEMBL8888079 | 0.81 | HMGB1 (0.54) | LMNAALDH1A1KDM4EHSD17B10GABRA1 | |
| SCHEMBL9755152 | 0.79 | LMNA (0.53) | LMNATSHRALDH1A1MITFMAPT | |
| SCHEMBL28452243 | 0.79 | GABRA1 (0.57) | LMNATSHRALDH1A1MITFMAPT | |
| SCHEMBL6200533 | 0.78 | LMNA (0.33) | LMNATSHRALDH1A1MITFMAPT | |
| Dimethyl Phthalate SCHEMBL632000 | 0.77 | TSHR (0.55) | LMNATSHRALDH1A1MAPTKDM4E | |
| SCHEMBL6274458 | 0.75 | ALDH1A1 (0.51) | LMNATSHRALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602277-A | Substituted benzene derivatives useful as neuraminidase inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 1997-02-11 | — | — | US | disclosed |
| WO-1996030329-A1 | SUBSTITUTED BENZENE DERIVATIVES USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INCORPORATED (US) | 1996-10-03 | — | — | WO | disclosed |