Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28452243 | 0.89 | GABRA1 (0.57) | LMNATSHRALDH1A1KDM4EPOLB | |
| SCHEMBL4412800 | 0.89 | ALDH1A1 (0.54) | LMNATSHRALDH1A1KDM4EPOLB | |
| SCHEMBL14408669 | 0.85 | CALM1 (0.47) | LMNATSHRALDH1A1CA1CA2 | |
| SCHEMBL6274458 | 0.84 | ALDH1A1 (0.51) | LMNATSHRALDH1A1KDM4EPOLB | |
| SCHEMBL1538293 | 0.84 | TSHR (0.65) | LMNATSHRALDH1A1KDM4EPOLB | |
| SCHEMBL1548509 | 0.83 | KDM4E (0.48) | LMNATSHRALDH1A1KDM4EPOLB | |
| SCHEMBL70322 | 0.82 | ALDH1A1 (0.66) | LMNATSHRALDH1A1KDM4EPOLB | |
| SCHEMBL6274334 | 0.82 | MEN1 (0.55) | LMNATSHRALDH1A1KDM4EKMT2A | |
| SCHEMBL8383960 | 0.82 | ALDH1A1 (0.49) | LMNATSHRALDH1A1KDM4EPOLB | |
| SCHEMBL3667908 | 0.81 | CA1 (0.52) | LMNATSHRALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991006589-A1 | NEW ANTI-HIV COMPOUNDS BELONGING TO AURINTRICARBOXYLIC ACID | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE (US) | 1991-05-16 | — | — | WO | disclosed |