Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.37 |
| ▸ | MCTS1 | Q9ULC4 | 2/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | BUB1 | O43683 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8887601 | 0.87 | LMNA (0.48) | KMT2AMEN1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL8889377 | 0.80 | LMNA (0.48) | KMT2AMEN1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL8889588 | 0.79 | CYP1A2 (0.49) | KMT2AMEN1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL8889202 | 0.76 | CYP1A2 (0.41) | KMT2AMEN1MAPT | |
| SCHEMBL8890203 | 0.74 | CYP1A2 (0.47) | MAPT | |
| SCHEMBL8889716 | 0.70 | PDE4A (0.52) | KMT2AMEN1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL8889113 | 0.70 | CYP1A2 (0.50) | KMT2AMEN1SMN1; SMN2LMNAMAPT | |
| SCHEMBL8889460 | 0.69 | MEN1 (0.48) | KMT2AMEN1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL8886943 | 0.68 | LMNA (0.49) | KMT2AMEN1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL8193845 | 0.68 | PDE3A (0.56) | SMN1; SMN2LMNANR1H2NR1H3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997001551-A1 | PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-16 | — | — | WO | disclosed |