Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7806788 | 0.87 | LMNA (0.39) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL9018857 | 0.85 | CYP1A2 (0.44) | LMNASMN1; SMN2CYP1A2ALDH1A1KDM4E | |
| SCHEMBL18978202 | 0.84 | KDM4E (0.39) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL14878888 | 0.80 | L3MBTL1 (0.49) | LMNAL3MBTL1CYP1A2ALDH1A1KDM4E | |
| SCHEMBL14782540 | 0.77 | LMNA (0.52) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL439716 | 0.74 | LMNA (0.59) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL423183 | 0.74 | PDE2A (0.61) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL8656719 | 0.72 | LMNA (0.48) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL6386090 | 0.72 | LMNA (0.48) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL401292 | 0.72 | LMNA (0.54) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8301855-A | — | — | None | — | — | JP | disclosed |
| US-5681957-A | DIAZOTIZATION OF (UN)SUBSTITUTED 2-AMINOPYRIMIDINES IN AQUEOUS HYDROGEN FLUORIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-28 | — | — | US | disclosed |
| US-5627056-A | PHYTOSPHINGOSINE CERAMIDE | ELIZABETH ARDEN CO., DIVISION OF CONOPCO, INC. (US) | 1997-05-06 | — | — | US | disclosed |
| JP-H08301855-A | PRODUCTION OF SUBSTITUTED 2-FLUOROPYRIMIDINE | BAYER AG | 1996-11-19 | — | — | JP | disclosed |
| EP-0742212-A1 | Process for the preparation of substituted 2-fluoro-pyrimidine | BAYER AG (DE) | 1996-11-13 | — | — | EP | disclosed |
| US-5527763-A | HIGHLY SAFE TO CROP PLANTS | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-06-18 | — | — | US | disclosed |
| US-5418212-A | Alkanoic acid amide derivative or its salt, and herbicidal composition | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-05-23 | — | — | US | disclosed |
| US-5411934-A | Alkanoic acid amide derivative or its salt, process for producing the same and herbicidal composition | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0581960-A1 | PYRIMIDINE OR TRIAZINE DERIVATIVE AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-02-09 | — | — | EP | disclosed |
| EP-0514551-A1 | ALKANAMIDE DERIVATIVE, ITS SALT, PRODUCTION THEREOF, AND HERBICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1992-11-25 | — | — | EP | disclosed |