Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | CASP6 | P55212 | 2/20 | 0.41 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8683165 | 1.00 | MEN1 (0.43) | MEN1POLBKMT2APSMB5PSMB1 | |
| SCHEMBL7343248 | 0.92 | POLB (0.45) | MEN1POLBKMT2AALDH1A1HPGD | |
| SCHEMBL7343264 | 0.92 | POLB (0.45) | MEN1POLBKMT2AALDH1A1HPGD | |
| SCHEMBL7437142 | 0.91 | HPGD (0.46) | PSMB5PSMB1PSMB2PTPN1ALDH1A1 | |
| SCHEMBL7437151 | 0.91 | HPGD (0.46) | PSMB5PSMB1PSMB2PTPN1ALDH1A1 | |
| SCHEMBL7303784 | 0.90 | ALDH1A1 (0.49) | MEN1POLBKMT2APSMB5PSMB1 | |
| SCHEMBL7303797 | 0.90 | ALDH1A1 (0.49) | MEN1POLBKMT2APSMB5PSMB1 | |
| SCHEMBL7435258 | 0.89 | GPR34 (0.47) | MEN1POLBKMT2APSMB5PSMB1 | |
| SCHEMBL7435245 | 0.89 | GPR34 (0.47) | MEN1POLBKMT2APSMB5PSMB1 | |
| SCHEMBL7441573 | 0.88 | POLB (0.40) | MEN1POLBKMT2AALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639783-A | POTENT PROTEASE INHIBITOR FOR TREATING MUSCULAR, NERVOUS SYSTEM DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-06-17 | — | — | US | disclosed |