Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8887039 | 0.83 | ALDH1A1 (0.60) | MAPK14HPGDALDH1A1NPC1RAB9A | |
| SCHEMBL17279850 | 0.82 | ALDH1A1 (0.50) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8888462 | 0.81 | IDO1 (0.55) | HTR7MAPK14HPGDALDH1A1NPC1 | |
| SCHEMBL8888803 | 0.81 | MAPK13 (0.48) | HTR7MAPK14HPGDALDH1A1NPC1 | |
| SCHEMBL30639606 | 0.81 | HTR7 (0.46) | HTR7MAPK14HPGDALDH1A1NPC1 | |
| SCHEMBL8888676 | 0.81 | GAA (0.52) | MAPK14HPGDALDH1A1NPC1RAB9A | |
| SCHEMBL8888906 | 0.81 | FGFR1 (0.48) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28616557 | 0.78 | HTR7 (0.43) | HTR7MAPK14HPGDALDH1A1NPC1 | |
| SCHEMBL8887278 | 0.77 | GABRA1 (0.46) | MAPK14HPGDALDH1A1NPC1RAB9A | |
| SCHEMBL8887485 | 0.77 | TTK (0.53) | HPGDSMN1; SMN2GAAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997001551-A1 | PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-16 | — | — | WO | disclosed |