Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8887630 | 0.81 | HTR7 (0.46) | NOTUMIDO1KDM4ENPC1ALDH1A1 | |
| SCHEMBL8887485 | 0.80 | TTK (0.53) | FGFR1KDM4EGAAHPGDSMN1; SMN2 | |
| SCHEMBL8887039 | 0.79 | ALDH1A1 (0.60) | IDO1KDM4ENPC1ALDH1A1GAA | |
| SCHEMBL8889130 | 0.79 | FGFR1 (0.47) | FGFR1NOTUMIDO1SMN1; SMN2NISCH | |
| SCHEMBL17279850 | 0.78 | ALDH1A1 (0.50) | IDO1KDM4ENPC1ALDH1A1GAA | |
| SCHEMBL8888803 | 0.78 | MAPK13 (0.48) | NOTUMIDO1KDM4ENPC1ALDH1A1 | |
| SCHEMBL8888462 | 0.78 | IDO1 (0.55) | NOTUMIDO1KDM4ENPC1ALDH1A1 | |
| SCHEMBL8888676 | 0.77 | GAA (0.52) | NOTUMNPC1ALDH1A1GAAHPGD | |
| SCHEMBL8889663 | 0.75 | CYP1A2 (0.47) | FGFR1NOTUMIDO1KDM4EALDH1A1 | |
| SCHEMBL19198811 | 0.75 | FGFR1 (0.65) | FGFR1NOTUMIDO1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997001551-A1 | PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-16 | — | — | WO | disclosed |