Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 4/20 | 0.53 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.49 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8888676 | 0.85 | GAA (0.52) | TP53SMN1; SMN2GAATDP1KMT2A | |
| SCHEMBL8887278 | 0.82 | GABRA1 (0.46) | SMN1; SMN2MAPTGAAKDM4ERXRA | |
| SCHEMBL8889422 | 0.80 | TTK (0.52) | TTKFGFR2FGFR3TP53SMN1; SMN2 | |
| SCHEMBL8888906 | 0.80 | FGFR1 (0.48) | FGFR2FGFR3TP53SMN1; SMN2FGFR1 | |
| SCHEMBL8887630 | 0.77 | HTR7 (0.46) | SMN1; SMN2MAPTGAAKDM4ETDP1 | |
| SCHEMBL8888641 | 0.77 | MAPT (0.46) | TTKFGFR2FGFR3TP53SMN1; SMN2 | |
| SCHEMBL8887039 | 0.76 | ALDH1A1 (0.60) | TTKTP53SMN1; SMN2MAPTGAA | |
| SCHEMBL17279850 | 0.75 | ALDH1A1 (0.50) | TTKSMN1; SMN2MAPTGAAKDM4E | |
| SCHEMBL8888803 | 0.75 | MAPK13 (0.48) | TP53SMN1; SMN2MAPTGAAKDM4E | |
| SCHEMBL8888462 | 0.75 | IDO1 (0.55) | TP53SMN1; SMN2MAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997001551-A1 | PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-16 | — | — | WO | disclosed |