Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TTK | P33981 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8886941 | 0.88 | NR1H2 (0.49) | MAPTGAATP53SMN1; SMN2KDM4E | |
| SCHEMBL8889202 | 0.86 | CYP1A2 (0.41) | MAPTTP53TTKCYP1A2MEN1 | |
| SCHEMBL8888264 | 0.85 | CYP1A2 (0.44) | MAPTGAATP53SMN1; SMN2CYP1A2 | |
| SCHEMBL8889663 | 0.83 | CYP1A2 (0.47) | MAPTGAATP53SMN1; SMN2KDM4E | |
| SCHEMBL10967551 | 0.82 | MAPT (0.60) | MAPTGAATP53SMN1; SMN2TTK | |
| SCHEMBL8889732 | 0.82 | CYP1A2 (0.41) | MAPTTP53SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL8887621 | 0.82 | CYP1A2 (0.50) | MAPTTP53SMN1; SMN2TDP1KDM4E | |
| SCHEMBL8890194 | 0.79 | CYP1A2 (0.50) | GAASMN1; SMN2KDM4ECYP1A2HPGD | |
| SCHEMBL8888361 | 0.79 | CYP1A2 (0.50) | MAPTTP53CYP1A2HPGD | |
| SCHEMBL8887885 | 0.79 | CYP1A2 (0.50) | MAPTGAATP53SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997001551-A1 | PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-16 | — | — | WO | disclosed |