Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889051 | 0.88 | LMNA (0.60) | LMNATP53CYP1A2GAAMAPT | |
| SCHEMBL8888641 | 0.88 | MAPT (0.46) | TP53CYP1A2GAASMN1; SMN2MAPT | |
| SCHEMBL8888264 | 0.88 | CYP1A2 (0.44) | NR1H2NR1H3LMNATP53CYP1A2 | |
| SCHEMBL8889732 | 0.85 | CYP1A2 (0.41) | NR1H2NR1H3LMNATP53CYP1A2 | |
| SCHEMBL8887621 | 0.84 | CYP1A2 (0.50) | LMNATP53CYP1A2MAPK14SMN1; SMN2 | |
| SCHEMBL8889202 | 0.83 | CYP1A2 (0.41) | TP53CYP1A2MAPTKMT2AMEN1 | |
| SCHEMBL8890194 | 0.82 | CYP1A2 (0.50) | CYP1A2MAPK13RAF1MAPK12MAPK11 | |
| SCHEMBL8887885 | 0.82 | CYP1A2 (0.50) | LMNATP53CYP1A2MAPK13RAF1 | |
| SCHEMBL8888361 | 0.82 | CYP1A2 (0.50) | TP53CYP1A2MAPK13RAF1MAPK12 | |
| SCHEMBL8889663 | 0.81 | CYP1A2 (0.47) | LMNATP53CYP1A2GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997001551-A1 | PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-16 | — | — | WO | disclosed |