Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.41 |
| ▸ | CDK4 | P11802 | 2/20 | 0.41 |
| ▸ | CCND1 | P24385 | 2/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8887621 | 0.87 | CYP1A2 (0.50) | KMT2AMEN1LMNACYP1A2GPR119 | |
| SCHEMBL8888295 | 0.87 | CYP1A2 (0.53) | KMT2AMEN1LMNACYP1A2NR1H2 | |
| SCHEMBL8889051 | 0.86 | LMNA (0.60) | KMT2AMEN1LMNACYP1A2ALDH1A1 | |
| SCHEMBL8890383 | 0.83 | CYP1A2 (0.51) | KMT2AMEN1LMNACYP1A2GPR119 | |
| SCHEMBL8889484 | 0.82 | CYP1A2 (0.53) | KMT2AMEN1LMNACYP1A2GPR119 | |
| SCHEMBL8889044 | 0.80 | CYP1A2 (0.62) | KMT2AMEN1LMNACYP1A2GPR119 | |
| SCHEMBL8890194 | 0.80 | CYP1A2 (0.50) | CYP1A2GPR119ALDH1A1KDM4EHPGD | |
| SCHEMBL8888361 | 0.80 | CYP1A2 (0.50) | CYP1A2GPR119HPGDMAPTTP53 | |
| SCHEMBL8887885 | 0.80 | CYP1A2 (0.50) | LMNACYP1A2GPR119ALDH1A1KDM4E | |
| SCHEMBL8889663 | 0.79 | CYP1A2 (0.47) | KMT2AMEN1LMNACYP1A2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997001551-A1 | PYRAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-16 | — | — | WO | disclosed |