Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 3/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 5/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893012 | 0.85 | ADRA2A (0.47) | NPY5RADRA2AMCHR1 | |
| SCHEMBL8893524 | 0.81 | NPY5R (0.70) | NPY5RNPY1RACHE | |
| SCHEMBL6039582 | 0.81 | NPY5R (0.70) | NPY5RNPY1RACHE | |
| SCHEMBL8892545 | 0.81 | NPY5R (0.70) | NPY5RNPY1RACHE | |
| SCHEMBL13413775 | 0.81 | TUBB3 (0.63) | — | |
| SCHEMBL8890399 | 0.80 | CASP6 (0.52) | NPY5RNPY1RACHE | |
| Hydrochloric Acid SCHEMBL8892586 | 0.80 | NPY5R (0.68) | NPY5RNPY1RACHE | |
| SCHEMBL30454981 | 0.79 | BCHE (0.56) | NPY5RADRA2AACHEMCHR1 | |
| Hydrochloric Acid SCHEMBL3938441 | 0.76 | APP (0.53) | NPY5RADRA2AACHE | |
| SCHEMBL8890767 | 0.76 | POLB (0.61) | NPY5RNPY1RACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020821-A1 | HETEROARYL DERIVATIVES | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |