Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 2/20 | 0.37 |
| ▸ | FNTB | P49356 | 2/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890920 | 0.88 | L3MBTL1 (0.49) | L3MBTL1GRM2HSD11B1FNTAFNTB | |
| SCHEMBL7462601 | 0.85 | PRSS1 (0.41) | GRM2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7466571 | 0.85 | SMN1; SMN2 (0.38) | GRM2NPC1RAB9ASMN1; SMN2CTSL | |
| SCHEMBL8451456 | 0.84 | SIGMAR1 (0.44) | L3MBTL1GRM2HRH3 | |
| SCHEMBL8457744 | 0.84 | SIGMAR1 (0.44) | L3MBTL1GRM2HRH3 | |
| SCHEMBL8452739 | 0.84 | SIGMAR1 (0.44) | L3MBTL1GRM2HRH3 | |
| SCHEMBL8891751 | 0.83 | FNTA (0.45) | L3MBTL1GRM2FNTAFNTBPGGT1B | |
| SCHEMBL7462288 | 0.81 | LMNA (0.40) | — | |
| SCHEMBL8450620 | 0.79 | GRM2 (0.42) | L3MBTL1GRM2FNTAFNTBPGGT1B | |
| SCHEMBL8458262 | 0.76 | GRM2 (0.42) | L3MBTL1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697408-B1 | 1 substituted-phenyl-oxazolidene-2-one derivatives and their use as adhesion-receptor antagonists | MERCK PATENT GMBH (DE) | 2002-01-23 | — | — | EP | disclosed |
| EP-0697408-A1 | 1 substituted-phenyl-oxazolidene-2-one derivatives and their use as adhesion-receptor antagonists | MERCK PATENT GmbH (DE) | 1996-02-21 | — | — | EP | disclosed |