Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | PTPRB | P23467 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891578 | 0.94 | ALDH1A1 (0.39) | ALDH1A1POLBLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL8891743 | 0.93 | LMNA (0.45) | ALDH1A1POLBLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL8892041 | 0.92 | ALDH1A1 (0.48) | ALDH1A1POLBLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL8893258 | 0.91 | ALDH1A1 (0.47) | ALDH1A1POLBLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL8891419 | 0.89 | ALDH1A1 (0.36) | ALDH1A1POLBLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL8892248 | 0.87 | ALDH1A1 (0.35) | ALDH1A1POLBLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL8894247 | 0.86 | ALDH1A1 (0.39) | ALDH1A1POLBLMNAMAPK1ABCC9 | |
| SCHEMBL8892236 | 0.85 | ALDH1A1 (0.40) | ALDH1A1POLBLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL8891307 | 0.85 | LMNA (0.46) | ALDH1A1POLBLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL8891930 | 0.84 | ALDH1A1 (0.40) | ALDH1A1POLBLMNAMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607976-A | ANNTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |