Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | KCNB1 | Q14721 | 3/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891930 | 0.93 | ALDH1A1 (0.40) | ALDH1A1POLBLMNASMN1; SMN2MAPK1 | |
| SCHEMBL8890655 | 0.92 | LMNA (0.46) | ALDH1A1POLBLMNASMN1; SMN2MAPK1 | |
| SCHEMBL8891702 | 0.91 | ALDH1A1 (0.48) | ALDH1A1POLBLMNASMN1; SMN2MAPK1 | |
| SCHEMBL8890927 | 0.91 | ALDH1A1 (0.46) | ALDH1A1POLBLMNASMN1; SMN2MAPK1 | |
| SCHEMBL8890057 | 0.88 | NPC1 (0.37) | ALDH1A1POLBLMNASMN1; SMN2MAPK1 | |
| SCHEMBL8893286 | 0.86 | ALDH1A1 (0.40) | ALDH1A1POLBLMNASMN1; SMN2MAPK1 | |
| SCHEMBL8892423 | 0.85 | NPC1 (0.35) | ALDH1A1POLBLMNASMN1; SMN2MAPK1 | |
| SCHEMBL8890853 | 0.85 | L3MBTL1 (0.41) | ALDH1A1POLBLMNAABCC9ABCC8 | |
| SCHEMBL8891396 | 0.85 | ALDH1A1 (0.46) | ALDH1A1ABCC9ABCC8KCNJ11KMT2A | |
| SCHEMBL8893099 | 0.85 | POLB (0.41) | ALDH1A1POLBLMNASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607976-A | ANNTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |