Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | PTGFR | P43088 | 2/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 2/20 | 0.38 |
| ▸ | KMO | O15229 | 2/20 | 0.38 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901022 | 0.90 | ADORA3 (0.44) | PTGFRNEU3ADORA2AADORA1ADORA3 | |
| Trifluoroacetic Acid SCHEMBL8901207 | 0.86 | ALDH1A1 (0.40) | PTGFRATRNEU3ADORA2AADORA1 | |
| SCHEMBL8892711 | 0.85 | KEAP1 (0.46) | TP53MAPTHDAC2 | |
| SCHEMBL8891817 | 0.83 | ADORA3 (0.44) | NEU3ADORA3MAPT | |
| SCHEMBL8891736 | 0.82 | ADORA3 (0.46) | NEU3ADORA3MAPTHDAC1 | |
| SCHEMBL8891755 | 0.82 | PTGFR (0.41) | PTGFRNEU3ADORA3MAPTHDAC1 | |
| Trifluoroacetic Acid SCHEMBL8902577 | 0.82 | KEAP1 (0.42) | TP53MAPTHDAC2 | |
| Trifluoroacetic Acid SCHEMBL8894608 | 0.80 | ADORA3 (0.40) | NEU3ADORA3TP53MAPTPIK3CA | |
| Trifluoroacetic Acid SCHEMBL8891099 | 0.80 | ADORA3 (0.41) | NEU3ADORA3MAPT | |
| SCHEMBL8892526 | 0.79 | ADORA3 (0.47) | NEU3ADORA2AADORA1ADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997033872-A1 | ANTI-VIRAL 4-ACYLAMINO-3-[IMIDAZOL-I-YL]-BENZOIC ACID DERIVATIVES | BIOTA SCIENTIFIC MANAGEMENT PTY. LTD. (AU) | 1997-09-18 | — | — | WO | claimed |
| WO-1997033872-A1 | ANTI-VIRAL 4-ACYLAMINO-3-[IMIDAZOL-I-YL]-BENZOIC ACID DERIVATIVES | BIOTA SCIENTIFIC MANAGEMENT PTY. LTD. (AU) | 1997-09-18 | — | — | WO | disclosed |