Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892077 | 0.89 | ITGB3 (0.43) | ITGB3ITGA2BHPGD | |
| SCHEMBL8893028 | 0.89 | ITGB3 (0.43) | ITGB3ITGA2BCA1CA2CA7 | |
| SCHEMBL8891751 | 0.88 | FNTA (0.45) | ITGB3ITGA2BGRM2POLBHRH1 | |
| SCHEMBL8891722 | 0.87 | ITGB3 (0.36) | ITGB3ITGA2BCA1CA2CA7 | |
| SCHEMBL7457894 | 0.85 | MAOA (0.36) | ITGB3ITGA2BGRM2KMT2A | |
| SCHEMBL8894919 | 0.85 | ITGB3 (0.40) | ITGB3ITGA2BHPGDGRM2TMEM97 | |
| SCHEMBL8892340 | 0.84 | MEN1 (0.42) | ITGB3ITGA2BCA1CA2CA7 | |
| SCHEMBL8894032 | 0.83 | ITGB3 (0.45) | ITGB3ITGA2B | |
| SCHEMBL7457368 | 0.80 | ITGB3 (0.41) | ITGB3ITGA2BTMEM97SIGMAR1ALDH1A1 | |
| SCHEMBL7467006 | 0.80 | ITGB3 (0.36) | ITGB3ITGA2BGRM2SIGMAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |