Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 6/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890815 | 0.91 | ABCC9 (0.32) | — | |
| SCHEMBL8892055 | 0.90 | HTT (0.36) | — | |
| SCHEMBL8892721 | 0.88 | IDH1 (0.35) | PTPRB | |
| SCHEMBL8891439 | 0.86 | PTPRB (0.40) | PTPRB | |
| SCHEMBL8892874 | 0.85 | ALDH1A1 (0.38) | PTPRB | |
| SCHEMBL8892801 | 0.84 | L3MBTL1 (0.35) | PTPRB | |
| SCHEMBL8892371 | 0.84 | — | — | |
| SCHEMBL8891389 | 0.84 | — | — | |
| SCHEMBL8890891 | 0.83 | KEAP1 (0.37) | PTPRB | |
| SCHEMBL8891118 | 0.82 | ALDH1A1 (0.36) | PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607976-A | ANNTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |